Boc-Ethanolamine CASNO: 26690-80-2

Key Physical Properties:

Appearance: Viscous liquid, colorless to light yellow

Molecular Weight: 161.20 g/mol

Formula: 𝐶7𝐻15𝑁𝑂3 (or) (𝐶𝐻3)3𝐶𝑂𝐶𝑂𝑁𝐻𝐶𝐻2𝐶𝐻2𝑂𝐻

Density: 1.042g/mL at25C (ltr) or 1.047g/cm3

Refractive Index: 𝑛20/𝐷 1.449(lit.)

Boiling Point: ∼267C

Flash Point: ∼115C

Storage: Recommended at 2−8C (or room temperature in a cool, dark place), protect from light

Solubility: Soluble in organic solvents such as dichloromethane and methanol.

N-Boc-ethanolamine acts as a versatile cross-linking reagent and is a commonly used building block in peptide synthesis and the creation of bifunctional molecules.

Boc-ethanolamine (CAS 26690-80-2), Is a viscous liquid used as a cross-linking reagent, commonly referred to as N-Boc-ethanolamine, tert-Butyl N-(2-hydroxyethyl)carbamate, or Boc-glycinol. It acts as a protected amino alcohol with a molecular formula of 𝐶7𝐻15𝑁𝑂3

Primary Synonyms for 26690-80-2:

N-Boc-ethanolamine

tert-Butyl N-(2-hydroxyethyl)carbamate

N-(tert-Butoxycarbonyl)ethanolamine

Boc-glycinol

2-(Boc-amino)-1-ethanol

N-(2-Hydroxyethyl)carbamic acid tert-butyl ester

2-(tert-Butoxycarbonylamino)ethanol

2-Boc-ethanolamine

N-Boc-aminoethanol

Boc-Gly-ol

2-t-Butoxycarbonylaminoethanol

N-Boc-ethanolamine (CAS 26690-80-2), Is a protected, bifunctional amino alcohol used heavily in pharmaceutical research, peptide synthesis, and chemical manufacturing. It acts as a key intermediate for building complex molecules, including prodrugs, sphingosine analogs, and phospholipids, while also serving as a cross-linking agent in polymer chemistry.

Key Applications and Uses:

Pharmaceutical Synthesis & Drug Discovery: It is used in the synthesis of complex organic compounds, particularly in creating prodrugs to improve the bioavailability of active pharmaceutical ingredients. It serves as a building block for pharmaceuticals, including the synthesis of lipids and sphingosine derivatives.

Peptide & Organic Synthesis: As a protected amine, it provides stability and allows for selective functionalization of the hydroxyl group in complex, multi-step reactions.

Chemical Reagent: It acts as a cross-linking agent and a building block in synthetic chemistry.

Material Science: Used in the development of functional polymers.

Safety: Causes skin and serious eye irritation, and is harmful if swallowed.

It is frequently referred to in chemical catalogs as N-Boc-ethanolamine, 2-(Boc-amino) ethanol, or tert-butyl (2-hydroxyethyl) carbamate.

 

What is Boc-Ethanolamine?

Boc-Ethanolamine is a protected amino alcohol used in organic and peptide synthesis.

What is the CAS number of Boc-Ethanolamine?

The CAS number of Boc-Ethanolamine is 26690-80-2.

What are the uses of Boc-Ethanolamine?

It is mainly used in peptide synthesis, pharmaceutical research, and organic chemical reactions.

What is the purity of Boc-Ethanolamine?

It is typically available in 98% or higher purity, depending on the supplier.

Is Boc-Ethanolamine suitable for research use?

Yes, it is widely used in laboratories for synthesis and drug development.

FAQs

What is Boc-Ethanolamine?

Boc-Ethanolamine is a protected amino alcohol used in organic and peptide synthesis.

What is the CAS number of Boc-Ethanolamine?

The CAS number of Boc-Ethanolamine is 26690-80-2.

What are the uses of Boc-Ethanolamine?

It is mainly used in peptide synthesis, pharmaceutical research, and organic chemical reactions.

What is the purity of Boc-Ethanolamine?

It is typically available in 98% or higher purity, depending on the supplier.

Is Boc-Ethanolamine suitable for research use?

Yes, it is widely used in laboratories for synthesis and drug development.