Uses and Applications

Peptide Synthesis: It is frequently used as a building block for the N-terminal pyro glutamylation of peptides, providing protection against amino peptidases. The Boc group allows for selective deprotection.

Pharmaceutical Intermediates: Used in the synthesis of specialized APIs (Active Pharmaceutical Ingredients), particularly antibiotics and other complex peptide therapeutics.

Chiral Building Block: Employed in the synthesis of biologically active compounds and unnatural amino acids (e.g., Proline – templated glutamic acid).

Cosmetics and Skincare: Used in the development of personal care products, often acting as a specialized component.

Flavoring and Fragrance Agents: Used as an intermediate in the production of unique scent and flavor compounds.

Handling and Stability

Stability: Stable under standard laboratory conditions.

Hazard Identification: The substance is typically classified with hazard codes related to skin/eye irritation and, depending on the supplier, can be labeled with toxic (Xn) and environmental (N) danger signs.

Precautions: Avoid exposure to air, moisture, and excessive heat.

Boc-L-Pyro glutamic Acid Methyl Ester (CAS: 108963-96-8) is a protected derivative of L-pyro glutamic acid, commonly used in organic synthesis, particularly for peptide synthesis and pharmaceutical intermediate production. It exists as a white to off-white solid, with a Boc (tert-butyloxycarbonyl) protecting group on the nitrogen and a methyl ester, which increases its solubility in organic solvents