Boc-D-Serine CASNO:6368-20-3

Physical properties:

Molecular Formula: C8H15NO5

Molecular Weight: 205.21 g/mol

Appearance: White to Almost powder crystal

Density: 1.2-1.3 g/cm3

Melting Point: 91-95°C

Solubility: Soluble in Water and slightly soluble in methanol

Optical Rotation:  +7.0 to +10.0 deg(C=2, H2O)

Synonyms:

  • Boc-D-Ser-OH
  • N-Boc-D-serine
  • Boc-D-Serine
  • N-tert-Butoxycarbonyl-D-serine
  • N-t-Boc-D-Serine
  • N-t-butyloxycarbonyl-D-serine

 

 

 

Category: Tags: ,

Uses:

  • Peptide Synthesis:Boc-D-Serine CASNO:6368-20-3, It is widely used in both solid-phase and solution-phase peptide synthesis. The “Boc” group acts as a protective shield for the amino group, preventing unwanted side reactions while other parts of a peptide chain are being built.
  • Pharmaceutical Development: It is an essential intermediate for creating peptidomimetics(molecules that mimic natural peptides) and drug candidates. For example, it is used to synthesize Lacosamide derivatives, which are potent anticonvulsants.
  • Biomedical Research:
    • Neuroscience: Researchers study it for its role in modulating NMDA receptors, which are critical for memory and learning.
    • Enzyme Inhibitors: It is used to design inhibitors for various enzymes, such as cysteine proteases.
    • Bioconjugation: It helps link biomolecules for drug delivery systems or diagnostic tools.
  • Chirality Studies: Because it is a specific chiral form (the “D” isomer), it is used to explore how the spatial arrangement of molecules affects biological systems.

 Key Applications:

  • Peptide Synthesis:Acts as a protected amino acid derivative (Boc-D-Ser-OH) in both solid and solution-phase synthesis.
  • Pharmaceutical Industry:Used in the synthesis of drugs, including anticonvulsants like Desacetyl Desmethyl Lacosamide.
  • Neuroscience Research:Utilized to study N-methyl-D-aspartate (NMDA) receptor modulation.
  • Biochemical Studies: Boc-D-Serine CASNO:6368-20-3,Used in research involving enzyme specificity, protein structure, and function.
  • Bioconjugation:Employed in linking biomolecules for drug delivery systems

 

What is Boc-D-Serine?
Boc-D-Serine is a protected amino acid derivative commonly used in peptide synthesis and organic chemistry.
What is the CAS number of Boc-D-Serine?
The CAS number of Boc-D-Serine is 6368-20-3.
What are the main uses of Boc-D-Serine?
It is widely used in peptide synthesis, pharmaceutical research, and the development of bioactive compounds.
Why is the Boc group used in Boc-D-Serine?
The Boc (tert-butyloxycarbonyl) group protects the amino group during chemical reactions, ensuring controlled and efficient synthesis.
What are the key properties of Boc-D-Serine?

It offers high purity, stability, and reliable reactivity, making it suitable for advanced chemical applications.

FAQs

What is Boc-D-Serine?
Boc-D-Serine is a protected amino acid derivative commonly used in peptide synthesis and organic chemistry.
What is the CAS number of Boc-D-Serine?
The CAS number of Boc-D-Serine is 6368-20-3.
What are the main uses of Boc-D-Serine?
It is widely used in peptide synthesis, pharmaceutical research, and the development of bioactive compounds.
Why is the Boc group used in Boc-D-Serine?
The Boc (tert-butyloxycarbonyl) group protects the amino group during chemical reactions, ensuring controlled and efficient synthesis.
What are the key properties of Boc-D-Serine?

It offers high purity, stability, and reliable reactivity, making it suitable for advanced chemical applications.