Physical properties:

N-BOC-4-Ethyl Piperidine Carboxylate (CAS 135716-09-5) is a white-to-off-white solid with the formula

𝐶14𝐻25𝑁𝑂4, commonly used as a building block in pharmaceutical synthesis. It acts as a protected piperidine derivative, featuring a tert-butyloxycarbonyl (Boc) group and an ethyl ester, often utilized for developing heterocyclic compounds.

Key Properties and Specifications:

• Molecular Formula: 𝐶14𝐻25𝑁𝑂4
• Molecular Weight: 271.35 g/mol
• CAS Number: 135716-09-5
• Appearance: White to off-white solid
• Storage: Stable under normal conditions; often stored in a cool, dry place
• Functional Groups: Contains ester and Boc-protected amine

Key Hazards:

• H302: Harmful if swallowed
• H312: Harmful in contact with skin
• H319: Causes serious eye irritation
• H332: Harmful if inhaled

Structure and Chemical Behavior:
The compound, also known as (1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid ethyl ester, features a piperidine ring substituted with a boc group and an ethylacetate chain. It is soluble in common organic solvents like dichloromethane or ethyl acetate.

N-Boc-4-ethyl piperidinecarboxylate (CAS 135716-09-5) is primarily known as Ethyl 1-Boc-4-piperidineacetate or 1-Boc-4-piperidineacetic acid ethyl ester. It is a piperidine derivative used in organic synthesis, featuring a tert-butyloxycarbonyl (Boc) protecting group, and is often used to produce pharmaceuticals.

Synonyms for CAS 135716-09-5:

Ethyl 1-[(1,1-dimethylethoxy)carbonyl]-4-piperidineacetate

4-(2-Ethoxy-2-oxoethyl)piperidine-1-carboxylic acid tert-butyl ester

1-Boc-4-(2-ethoxy-2-oxoethyl) piperidine

Ethyl N-Boc-4-piperidineacetate

4-Piperidineacetic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester

SCHEMBL785988

MFCD08275143

N-Boc-4-ethyl piperidinecarboxylate (CAS 135716-09-5) is primarily known as Ethyl 1-Boc-4-piperidineacetate or 1-Boc-4-piperidineacetic acid ethyl ester. It is a piperidine derivative used in organic synthesis, featuring a tert-butyloxycarbonyl (Boc) protecting group, and is often used to produce pharmaceuticals.

N-Boc-4-ethyl piperidinecarboxylate (CAS 135716-09-5), specifically indexed as (1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid ethyl ester, is a versatile heterocyclic building block used primarily in pharmaceutical synthesis. It acts as a protected piperidine derivative for constructing complex, bioactive molecules, often featuring in research for novel therapeutic agents.

Key Applications and Uses:

• Pharmaceutical Research: It serves as a key intermediate in the development of various drugs, particularly those targeting inflammatory diseases, autoimmune conditions, and neurological disorders.
• Enzyme Inhibition: It is used as a reagent in the preparation of inhibitors for tumor necrosis factor-alpha-converting enzyme (TACE).
• Sodium Channel Blockers: The compound is used in the synthesis of 3-amino-1-(5-indanyloxy)-2-propanol derivatives, which function as sodium channel blockers for potential stroke treatment.
• Organic Synthesis: It acts as a substrate in palladium-catalyzed 𝛼-arylation of esters with heterocyclic halides, enabling the formation of 4-pyridylpiperidinyl esters.

Chemical Building Block: The BOC (tert-butyloxycarbonyl) group provides stability under basic conditions, while the ester group allows for further functionalization, making it useful for constructing complex molecular architectur