Uses
- Intermediate: Used in the synthesis of pharmaceuticals, including Dabigatran, and as a precursor for adrenergic agonists.
- Research: Acts as a Glycine derivative.
Synonyms and Variations
- 2-(4-Cyanophenylamino)acetic acid
- [(4-Cyanophenyl)amino]acetic acid
- 4-(((Carboxy)methyl)amino)benzonitrile
- N-(p-Cyanophenyl)glycine
- 4-Cyanophenylaminoacetic acid
- 2-(4-cyanoanilino)acetic acid
- Glycine, N-(4-cyanophenyl)-
Safety and Usage
- Hazard Identification: Harmful if swallowed, in contact with skin, or if inhaled. It causes skin and serious eye irritation.
- Applications: Used as a pharmaceutical intermediate.
- Storage: Store at room temperature.
N-(4-Cyanophenyl)glycine (CAS 42288-26-6) is an aromatic amino acid derivative primarily used as a key pharmaceutical intermediate for synthesizing the anticoagulant drug Dabigatran etexilate. It functions as a, building block in organic synthesis and as an, impurity marker in, pharmaceutical research.
Key Uses and Applications
- Pharmaceutical Intermediate: Primary application is in the production of Dabigatran etexilate, a direct thrombin inhibitor used to treat blood clot-related disorders.
- Research & Development: Utilized in drug discovery and peptide chemistry as an unnatural amino acid derivative.
- Chemical Synthesis: Used as a building block for various organic compounds and potentially for developing specialized materials with high oxidative stability.
- Product Form: Appears as a white to off-white solid, often soluble in solvents like DMSO, methanol, and dichloromethane.
The CAS number is 42288-26-6, which uniquely identifies this compound. It is widely used in pharmaceutical manufacturing, agrochemical production, and laboratory research. The molecular formula is C₉H₈N₂O₂. Store in a cool, dry, and well-ventilated place in tightly closed containers, away from moisture and heat.
