Methanesulfonamide CASNO:3144-09-0

Physical properties:

Appearance: White to light yellow or orange powder, crystals, or flakes

Molecular FormulaCH5NO2S

Molecular Weight: 95.12 g/mol

Melting Point: 85-94°C

Boiling Point: 180°C-208°C

Solubility: Highly soluble in water and polar organic solvents like DMSO and methanol

Acidity (pKa): 10.87

Density : 1.0-1.23 g/cm3

Synonyms:

Methylsulfonamide

Mesylamide

Methanesulfonic Amide

Methanesulphonamide

Methyl Sulfonylamine

Aminosulfane dioxide

Methane sulfonamide

Category: Tags: ,

Uses:

  • Organic Synthesis:Methanesulfonamide CASNO:3144-09-0, It is used to synthesize important organic reagents, such as

(2-methylthio-1–toluenesulfonyl)methanesulfonamide and tutyl ((2-(trimethylsilyl) ethyl)sulfonyl)carbamate.

  • Nitrogen Source: It acts as a nitrogen source for converting carboxylic acids into their corresponding nitriles.
  • Catalysis: In Sharpless dihydroxylation, it functions as a catalyst during the final hydrolysis step to help form cis-vicinal-diols.
  • Solvent:Methanesulfonamide CASNO:3144-09-0, It is sometimes employed as a solvent in specific dihydroxylation reactions

 

Key Applications:

    • Chemical Synthesis:Acts as an intermediate for creating various compounds, including indole-N-acetamide derivatives and other pharmaceuticals.

3144-09-0 = 3,135

  • Pharmaceutical Research:Used in the development of drug candidates, such as pyrimidine-substituted 3,5-dihydroxy-6-heptenoates and the anti-inflammatory drug repertaxin.
  • Reagent in Laboratory Studies:Used in biochemical research to study protein-ligand complex binding affinities.
  • Materials Synthesis:Utilized in reactions involving thionyl chloride, cyanates, carbon disulfide, ketones, and aldehydes.

What is Methanesulfonamide?
Methanesulfonamide is an organic compound used as an intermediate in pharmaceuticals and chemical synthesis.
What is the CAS number of Methanesulfonamide?
The CAS number of Methanesulfonamide is 3144-09-0.
What are the applications of Methanesulfonamide?
It is commonly used in drug development, organic synthesis, and as a reagent in chemical research
Is Methanesulfonamide safe to handle?
Proper lab safety protocols should be followed; it may cause irritation if inhaled or in contact with skin.
What is the chemical formula of Methanesulfonamide?
The chemical formula of Methanesulfonamide is CH₃SO₂NH₂.  

FAQs

What is Methanesulfonamide?
Methanesulfonamide is an organic compound used as an intermediate in pharmaceuticals and chemical synthesis.
What is the CAS number of Methanesulfonamide?
The CAS number of Methanesulfonamide is 3144-09-0.
What are the applications of Methanesulfonamide?
It is commonly used in drug development, organic synthesis, and as a reagent in chemical research
Is Methanesulfonamide safe to handle?
Proper lab safety protocols should be followed; it may cause irritation if inhaled or in contact with skin.
What is the chemical formula of Methanesulfonamide?
The chemical formula of Methanesulfonamide is CH₃SO₂NH₂.