Properties
CAS Number: 6384-08-3
Molecular Formula: C6H11NO4
Molecular Weight: 161.16 g/mol
Appearance: White to almost white powder or crystals
Melting Point: 130–140°C
Storage: Refrigerated (0–10°C) and store under inert gas
Synonyms
L-Glutamic acid 𝛼-methyl ester
1-Methyl L-glutamate
Methyl (S)-2-amino-4-carboxybutanoate
(4S)-4-Amino-5-methoxy-5-oxopentanoic acid
L-Glu-OMe
Glutamic acid 1-methyl ester
Uses and Applications
Peptide Synthesis & Research: Serves as a key, protected building block in peptide synthesis and is used in metabolic, pharmaceutical, and neurochemical studies.
Specialized Applications: Utilized in cosmetic formulations for skin benefits, in agriculture to promote growth, and as a flavor enhancer.
Analytical Use: Acts as a reference standard in drug development QC and method validation.
Important Distinction
6384-08-3 is the 𝛼-methyl ester (1-methyl), which protects the carboxylic acid adjacent to the amine.
It should not be confused with L-Glutamic acid 𝛾 -methyl ester (5-methyl, CAS 1499-55-4) or the dimethyl ester (CAS 23150-65-4)
L-Glutamic acid methyl ester, specifically known as L-Glutamic acid 1-methyl ester or L-Glutamic acid
𝜶-methyl ester (CAS number 6384-08-3), is a derivative of the non-essential amino acid L-glutamic acid. It is widely used in biochemical research, peptide synthesis, and pharmaceutical development.