Boc-L-Valine CASNO:13734-41-3

Boc-L-Valine (CAS 13734-41-3) is a protected amino acid derivative commonly used in peptide synthesis and pharmaceutical manufacturing. It is the L-Valine amino acid with its amino group protected by a tert- butoxy carbonyl (Boc) group.

CAS Number: 13734-41-3 

Properties

Molecular Formula: 𝐶10𝐻19𝑁𝑂4

Molecular Weight: 217.26 g/mol

Appearance: White to off-white crystalline powder

Melting Range: 73.0–83.0 °C (lit.)

Purity: Typically >98% or >99% (HPLC)

Solubility: Soluble in common organic solvents like ethanol and DMF.

Synonyms

N-(tert- Butoxy carbonyl)-L-valine

Boc-Val-OH

N-Boc-L-valine

(S)-2-(tert -Butoxy carbonylamino)-3-methylbutanoic acid

N-tert- Butoxy carbonylvaline

 

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Uses and Applications

  • Peptide Synthesis: Used as an N-protected amino acid building block in solid-phase (SPPS) and liquid-phase peptide synthesis.
  • Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) such as Valacyclovir and Valganciclovir.
  • Drug Discovery: Used in research for developing proteasome inhibitors and other bioactive molecules.
  • Antimicrobial Studies: Acts as a precursor in compounds that show inhibitory activity against microbes like Helicobacter pylori and MRSA.
  • Biotechnology: Employed to produce modified proteins and enzymes. 

 

 

What is Boc-L-Valine?
Boc-L-Valine is a protected amino acid used in peptide synthesis, where the Boc group safeguards the amine functionality during reactions.
What is the CAS number of Boc-L-Valine?

The CAS number is 13734-41-3, which uniquely identifies this compound.

What are the main applications of Boc-L-Valine?

It is widely used in peptide synthesis, pharmaceutical research, and the production of active pharmaceutical ingredients (APIs).

How should Boc-L-Valine be stored?

It should be stored in a cool, dry place, in tightly sealed containers away from moisture and heat.

Is Boc-L-Valine suitable for laboratory research?

Yes, it is commonly used in research laboratories and industrial R&D applications.

FAQs

What is Boc-L-Valine?
Boc-L-Valine is a protected amino acid used in peptide synthesis, where the Boc group safeguards the amine functionality during reactions.
What is the CAS number of Boc-L-Valine?

The CAS number is 13734-41-3, which uniquely identifies this compound.

What are the main applications of Boc-L-Valine?

It is widely used in peptide synthesis, pharmaceutical research, and the production of active pharmaceutical ingredients (APIs).

How should Boc-L-Valine be stored?

It should be stored in a cool, dry place, in tightly sealed containers away from moisture and heat.

Is Boc-L-Valine suitable for laboratory research?

Yes, it is commonly used in research laboratories and industrial R&D applications.