Properties

CAS Number: 1145-76-2

Molecular Formula: C13H11NO3

Molecular Weight: 229.23 g/mol

Melting Point: 105.0 to 109.0 °C

Boiling Point: 386.2±17.0 °C (predicted)

Density: 1.232±0.06 g/cm³ (predicted)

Flash Point: 176 °C

Refractive Index: 1.603

Appearance: White to light yellow powder to crystal

Solubility: Soluble in common organic solvents, often used in organic synthesis (e.g., in Williamson ether synthesis mixtures)

Synonyms

1-(Benzyloxy)-4-nitrobenzene

p-(Benzyloxy)nitrobenzene

4-(Benzyloxy)nitrobenzene

Benzyl p-nitrophenyl ether

1-Nitro-4-(phenylmethoxy)benzene

[(4-Nitrophenoxy)methyl]benzene

Ether, benzyl p-nitrophenyl

NSC 24667 

Uses & Applications

• Organic Synthesis Intermediate: Used as a key intermediate in the synthesis of more complex organic molecules, specifically as a precursor to functionalized anilines.
• Chemical Building Block: Used in the development of specialized chemicals, dyes, and pigments.
• Research & Development: Employed in scientific research, including laboratories focusing on material science, chemical synthesis, and molecular biology.
• Model Studies: Used in studies involving Williamson ether synthesis (e.g., reaction of 4-nitrophenol with benzyl chloride).

Safety and Hazards

GHS Classification: Irritant (Xi).

Hazard Statements: Causes skin irritation (H315).

Precautionary Statements: P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362.

Storage

Recommended to be stored in a cool and dark place, often at room temperature (around 15°C to 25°C), or under 15°C for long-term stability, in a sealed container.

Benzyl-4-Nitrophenyl ether (CAS 1145-76-2), also known as 1-(benzyloxy) -4-nitrobenzene, is a chemical compound primarily used as an organic synthesis intermediate and building block in research and development. It is a solid, often appearing as white to light yellow crystals.