Common Synonyms and Identifiers:

Benzenesulfonamide

Benzene sulfonamide

Benzenesulfonyl amine

Benzene sulfonamide (various spellings: Benzene sulfonamtde, Benzosuifqnamide, Benzenesulfonamide)

Benzenesulphonamide

Benzolsulfonamide

Phenylsulfonamide

Benaenesulfonicamide

M and B 7973

NSC 5341

NSC 85506

MDL Number: MFCD00007930

Identifiers and Regulatory

EC Number: 202-637-1

Beilstein/REAXYS Number: 1100566

Benzenesulfonamide (CAS 98-10-2), Is a versatile aromatic compound primarily used as a key intermediate in the chemical, pharmaceutical, and agricultural industries. It acts as a structural building block for the synthesis of various compounds, including dyes, pesticides, and pharmaceuticals.

Key Applications and Uses:

Pharmaceutical Intermediate: It is a vital raw material in the synthesis of APIs (Active Pharmaceutical Ingredients), such as sulfonamide antibiotics and drugs for treating proliferative diseases like cancer. It is used specifically in the preparation of sulfacetamide.

Carbonic Anhydrase Inhibitor: The compound is recognized for its ability to inhibit human carbonic anhydrase B, making it relevant for medical research and the development of new treatments.

Chemical Synthesis: Used as a reagent in organic synthesis for creating heterocyclic compounds and performing sulfonylation reactions.

Industrial Applications:

Dyes & Photochemicals: Used in the manufacturing of dyes and photochemical agents.

Disinfectants: Applied in the production of disinfectant formulations.

Specialty Chemicals: Serves as an ingredient in the production of polymers and other specialized chemical products.

Research: Employed in laboratory settings to develop analytical methods for detecting environmental contaminants, such as benzothiazole and benzotriazole.

It is important to note that while it has antibacterial properties, it is primarily utilized as a precursor to more complex, biologically active molecules.