949-99-5

4-Nitro-L-Phenylalanine CASNO:949-99-5

Physical properties:

CAS Number: 949-99-5

Appearance: White to light yellow powder or crystals

Molecular Formula: C9H10N2O4

Molecular Weight: 210.19 g/mol

Melting Point: 236-2390C (decomposes)

Density: 1.408 g/cm3

Boiling Point: 414.1 (predicted)

Optical Rotation: +50 to +70

Solubility: Sparingly soluble in water

Flash Point: 204.20C

Specific Gravity: 1.4

Synonyms:

4-Nitro-L-phenylalanine

L-4-Nitrophenylalanine

P-Nitrophenylalanine

2-Amino-3-(4-nitrophenyl)propanoic acid

H-Phe(4-NO2)-OH

(2S)-2-amino-3-(4-nitrophenyl)propanoic acid

4-Nitro(L)phenylalanine

MDL Number: MFCD00051221

PubChem CID: 13706

4-Nitro-L-phenylalanine (CAS 949-99-5) is a non-proteinogenic amino acid used primarily as a research building block in protein engineering, drug development, and chemical synthesis. It is key for incorporating unnatural amino acids into proteins, studying enzyme mechanisms, and developing potential therapeutic agents, including tumor immunotherapy.

Key Applications:

Protein Engineering & Genetic Code Expansion: Used to modify protein structure and function by introducing unnatural amino acids via in vitro translation.

Drug Discovery & Medicinal Chemistry: Acts as an intermediate for synthesizing novel pharmaceuticals, specifically targeting enzymes or receptors. It has shown potential in antiviral and anti-inflammatory research, as well as inhibiting human leukemia cell growth.

Biochemical Assays: Employed as a reagent for measuring enzyme activity and studying neurotransmission.

Material Science: Incorporated into polymer matrices for specialized coatings and adhesives.

Vaccine Development: Utilized in creating NitraTh epitope-based neoantigen vaccines for immunotherapy.

Category: Tags: ,

FAQs

What is 4-Nitro-L-Phenylalanine?
4-Nitro-L-Phenylalanine is a chemical intermediate commonly used in pharmaceutical research, peptide synthesis, and specialty chemical applications.
What is the CAS number of 4-Nitro-L-Phenylalanine?

The CAS number of 4-Nitro-L-Phenylalanine is 949-99-5.

What are the applications of 4-Nitro-L-Phenylalanine?
It is widely used in pharmaceutical intermediates, biochemical research, peptide synthesis, and organic chemistry applications.
4-Nitro-L-Phenylalanine suitable for laboratory use?
Yes, 4-Nitro-L-Phenylalanine is commonly used in laboratories and research facilities for analytical and synthesis purposes.
How should 4-Nitro-L-Phenylalanine be stored?
It should be stored in a cool, dry, and well-sealed container away from moisture and direct sunlight to maintain stability and purity
What industries use 4-Nitro-L-Phenylalanine?
Pharmaceutical, biotechnology, chemical manufacturing, and research industries frequently use this compound in various applications.

Related products