4-Chloro-2-Methoxy Pyrimidine CASNO: 51421-99-9

4-Chloro-2-Methoxypyrimidine (CAS 51421-99-9) is a heterocyclic building block, specifically a pyrimidine derivative utilized frequently in chemical synthesis, particularly within the pharmaceutical and materials science industries.

Chemical Properties

CAS Number: 51421-99-9

Molecular Formula: 𝐶5𝐻5𝐶𝑙𝑁2𝑂

Molecular Weight: 144.56 g/mol

Appearance: White to yellow to orange to brown solid or semi-solid or liquid (hygroscopic)

Purity: Commonly 97% or higher

Melting/Boiling Points: Specific ranges vary by manufacturer but it generally presents as a low-melting solid or liquid at room temperature

Storage: Should be stored sealed, in a dry, cool environment, often recommended at 2−8∘𝐶

Synonyms

  • 4-Chloro-2-methoxypyrimidine
  • Pyrimidine, 4-chloro-2-methoxy- (9CI)
  • 4-Chloro-2-methoxy-pyrimidine
  • MDL Number: MFCD09025734
  • InChIKey: XCAMEGPUILTZSU-UHFFFAOYSA-N

 

 

 

Uses and Applications

4-Chloro-2-methoxypyrimidine acts as a versatile intermediate in organic synthesis:

  • Pharmaceutical Intermediates: It is used as a foundational building block for the synthesis of various pharmaceutical active ingredients.
  • Heterocyclic Chemistry: It is used in reactions requiring the modification of the pyrimidine ring, such as nucleophilic aromatic substitution of the 4-chloro group.
  • Research & Development: Used in laboratory synthesis for developing new heterocyclic compounds.

Safety and Hazards

GHS Classification:

Warning

H302: Harmful if swallowed

H315: Causes skin irritation

H319: Causes serious eye irritation

H335: May cause respiratory irritation

Precautions: P261 (Avoid breathing dust/fume/gas/mist/vapours/spray) and P280 (Wear protective gloves/protective clothing/eye protection/face protection) are recommended.

What is 4-Chloro-2-Methoxy Pyrimidine used for?

It is mainly used as a chemical intermediate in pharmaceutical manufacturing and fine chemical synthesis.

What is the CAS number of 4-Chloro-2-Methoxy Pyrimidine

The CAS number is 19355-69-2, which uniquely identifies this compound.

What industries use this compound?

It is widely used in pharmaceuticals, agrochemicals, and specialty chemical industries.

How should this chemical be handled safely?

It should be handled using appropriate protective equipment and safety procedures as per MSDS guidelines.

What are the recommended storage conditions?

Store in a cool, dry, and well-ventilated area, away from heat and incompatible substances.

Is bulk supply available?

Yes, it is available in bulk quantities with flexible packaging options to suit industrial requirements.

FAQs

What is 4-Chloro-2-Methoxy Pyrimidine used for?

It is mainly used as a chemical intermediate in pharmaceutical manufacturing and fine chemical synthesis.

What is the CAS number of 4-Chloro-2-Methoxy Pyrimidine

The CAS number is 19355-69-2, which uniquely identifies this compound.

What industries use this compound?

It is widely used in pharmaceuticals, agrochemicals, and specialty chemical industries.

How should this chemical be handled safely?

It should be handled using appropriate protective equipment and safety procedures as per MSDS guidelines.

What are the recommended storage conditions?

Store in a cool, dry, and well-ventilated area, away from heat and incompatible substances.

Is bulk supply available?

Yes, it is available in bulk quantities with flexible packaging options to suit industrial requirements.