Benzyl Chloro Methyl Ether (CAS 3587-60-8): Properties, Uses & Applications

About This Product:

CAS Number                   : 3587-60-8

Molecular Weight           : 156.61

Molecular Formula         : C₈H₉ClO

Synonym(s)                       :  Benzyloxymethyl Chloride
(Chloromethoxymethyl) benzene
BOM-Cl;BENZYL CHLOROMETHYL ETHER;
BENZYLOXYMETHYL CHLORIDE;
Chloromethyl benzyl ether; Benzylchloromethyl ether
;α-Chloromethoxytoluene;Benzlchloromethyl ether; Benzyylchloromethyl ether

Physical Properties:

Appearance                                      : Clear colorless to slight yellow liquid

Purity                                                 : >80.00% (GC)

Melting Point                                    : NA

Boiling Point                                      : 102°C at 14mmHg

Storage Temperature                     : 2 to 8°C Moisture sensitive closed and nitrogen atmosphere

LOD                                                      : NA

Solubility                                             : Soluble in chloroform, Ethyl acetate

Density                                                 : 1.126 g/mL at 20°C

Moisture content                                : NA

Description: Benzyl Chloro Methyl Ether (3587-60-8) It is a chloro alkyl ether. It is used as an alkylating agent in organic synthesis, it is used for introducing the benzyloxymethyl (BOM) protecting group, and is thus often called BOM-Cl or BOM chloride.

Uses:

• Protective Group Chemistry: Introduces the BOM protecting group (benzyloxymethyl) in complex organic synthesis, especially in asymmetric synthesis.
• Pharmaceuticals: Used in creating intermediates for active pharmaceutical ingredients (APIs) and in research for drug delivery systems.
• Polymer Chemistry: Acts as a coupling agent for specialty polymers, enhancing properties for coatings and adhesives, and in drug delivery scaffolds.
• Flavor & Fragrance: Helps synthesize aromatic compounds for flavors and fragrances.
• Research: Modifies biomolecules and serves as a general reagent for creating diverse organic compounds.

Key applications:

• Organic Synthesis & Protection:Benzyl Chloro Methyl Ether (CAS 3587-60-8), Used as an alkoxymethylation reagent for the protection and deprotection of alcohols, phenols, and carboxylic acids.
• Pharmaceutical Intermediates: Employed in the development and synthesis of active pharmaceutical ingredients (APIs).
• Polymer Chemistry: Acts as a coupling agent in the production of specialized polymers, including polystyrene and polyurethane, as well as materials for drug delivery systems and tissue engineering scaffolds.
• Chemical Manufacturing: Used in the synthesis of aromatic compounds, pesticides, dyes, and surfactants.
• Laboratory Research: Utilized for the modification of biomolecules and in bioconjugation techniques.