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4-Bromo-1-nitrobenzene (CAS No. 586-78-7): Properties, Applications, and Industrial Importance

By June 17, 2026 Blog

Introduction:

4-Bromo-1-nitrobenzene (CAS No. 586-78-7) Is an aromatic organic compound that has many applications, including use in the synthesis of pharmaceuticals, development of agrochemicals, and as an industrial chemical intermediate. This compound has unique properties due to its structure, characterized by the presence of nitro and bromine functional groups.

 This article provides information about 4-Bromo-1-nitrobenzene (CAS No. 586-78-7), including its physical and chemical properties, applications, and potential industrial uses. What is 4-Bromo-1-nitrobenzene? 

4-Bromo-1-nitrobenzene is an organic compound with the chemical formula C6H4BrNO2. 

It is a para-substituted aromatic compound with a nitro group and a bromine atom attached to a benzene ring. Chemical Information 4-Bromo-1-nitrobenzene; CAS No. 586-78-7; molecular formula C6H4BrNO2; molecular weight 202.01 g/mol, appearance yellow to pale yellow crystals; available in ≥ 99% purity. 

Physical and Chemical Properties of 4-Bromo-1-nitrobenzene 

It is important to have information about the physical and chemical properties of 4-Bromo-1-nitrobenzene (CAS 586-78-7). Key Properties 4-Bromo-1-nitrobenzene; molecular formula C6H4BrNO2; molecular weight 202.01 g/mol, CAS No. 586-78-7; appearance yellow crystalline; solubility slightly soluble in water; stability stable under recommended storage conditions.

The dual nature of the bromine and nitro groups in this compound makes it very versatile for use in a wide variety of substitution and coupling reactions.

Applications of 4-Bromo-1-nitrobenzene

 Pharmaceutical Intermediate

4-Bromo-1-nitrobenzene is one of the most widely used compounds as an intermediate material in the pharmaceutical industry to synthesise active pharmaceutical ingredients (APIs) and other advanced organic compounds.

 Agrochemical Production

The compound also has applications in agrochemical manufacture, whereby it is employed in the synthesis of pesticide, herbicide, and other crop protection chemicals.

 Organic Synthesis

4-Bromo-1-nitrobenzene (CAS 586-78-7) is commonly used by chemists in many different aspects of organic synthesis, including:

  • Suzuki coupling reactions
  •  Nucleophilic aromatic substitutions
  •  Reductions

 Bromination and other functional group transformations (oxidations or reductions)

Research & Development

Universities, research labs and chemical companies can also use the compound in the research and development of aromatic compounds and other advanced materials.

 Advantages of Using 4-Bromo-1-nitrobenzene

Good Reactivity

High reactivity of the bromine and nitro groups in this compound allows high-quality synthesis and consequently increased yields across multiple steps.

Useful Intermediate

This compound can be used as an intermediate in the synthesis of many different types of chemical compounds in both the pharmaceutical and industrial sectors.

Consistent Quality

The product is sold in high-purity grades of CAS 586-78-7.

Researchers and developers can thus be confident of reliable product quality.

  • Storage and Handling
  • Storage Recommendations
  • Keep in a dry, cool place 
  • Protect from light
  •  Keep in tightly closed containers
  •  Protect from contact with strong oxidizing agents

Handle pursuant to general laboratory safety guidelines Personal Protective Equipment

Worker should employ:

  • Protective gloves
  •  Safety glasses
  •  Protective laboratory clothing
  •  Respiration protection when warranted
  •  Consult most recent Safety Data Sheet (SDS)

 Industrial Relevance of CAS 586-78-7

The demand for 4-Bromo-1-nitrobenzene continues to grow due to its value to the specialized chemical manufacturing industry. This important compound is used to produce high-value intermediates for the pharmaceutical, agricultural and specialty chemical industries.

Its chemical stability, ease of availability and ease of handling by chemists around the world make it a highly-requested product for use by industrial manufacturers.

 Conclusion

4-Bromo-1-nitrobenzene (CAS No. 586-78-7), Is a high-value aromatic building block that is extensively used in pharmaceutical research, agrochemical manufacturing and organic synthesis projects. Its unique combination of functional groups allows for a wide variety of versatile types of chemistry, making it a highly sought-after intermediate to the modern day chemical industry.

Companies that require high-value 4-Bromo-1-nitrobenzene should look to acquire their product from a reputable vendor that offers consistently high purity, reliable documentation and adherence to all pertinent regulatory considerations.

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