Key Physical Properties:

• Formula: 𝐶3𝐻7𝐶𝑙𝑂
• Molecular Weight: 94.54g/mol
• Appearance: Colorless liquid
• Boiling Point: 82°C
• Density: 1.019g/mL
• Solubility: Insoluble in water
• Refractive Index: 𝑛20/𝐷 1.404
• Flash Point: Below 73°F (<22.7°C)

Safety and Hazards:

• Flash Point: Highly flammable; vapors may travel to ignition sources and flash back.
• Reactivity: Can polymerize explosively when heated.
• Health Hazards: Causes severe irritation to skin, eyes, and mucous membranes; may cause dizziness, pulmonary edema, or respiratory damage.

Chloromethyl ethyl ether (CAS 3188-13-4), Is a colorless, flammable, and toxic liquid used as a chemical intermediate.

. Key synonyms include (chloromethoxy) ethane, Ethoxychloromethane, Ethoxymethyl chloride, and Ethyl chloromethyl ether. 

Primary Synonyms for CAS 3188-13-4:

• (Chloromethoxy)ethane
• Ethoxychloromethane
• Ethoxymethyl chloride
• Ethyl chloromethyl ether
• Chloromethoxyethane
• Ether, chloromethyl ethyl

Key Identifiers & Properties:

• EC Number: 221-687-5
• Appearance: Colorless to light yellow liquid
• Hazards: Highly flammable, toxic by inhalation, ingestion, or skin absorption, and causes severe burns.

Chloromethyl ethyl ether (CAS 3188-13-4) is a highly reactive organic compound used primarily as a pharmaceutical intermediate, particularly for producing HIV-1 reverse transcriptase inhibitors and other fine chemicals. It is also used as an alkylating agent, a reagent for introducing protecting groups in organic synthesis, and in the production of specialized polymers.

Key Uses and Applications:

• Pharmaceutical Synthesis:It acts as a key intermediate in the synthesis of specialized pharmaceuticals, including compounds derived from TNK-651. It is also used to prepare 6-benzyl-1-(ethoxymethyl)-5-iodopyrimidine-2,4(1H,3H)-dione, an intermediate for MKC-442 analogues.
• Chemical Reagent:It is used as an alkylating and chloromethylating agent in organic synthesis, similar to chloromethyl methyl ether, to introduce the ethoxymethyl (EOM) group.
• Polymer Chemistry:It is employed in the manufacturing of special polymers to impart specific, tailored properties.
• Catalyst Production:It serves as a precursor in the preparation of acylation catalysts for alcohols, such as 1,3-bis-[(R)-1-(2-naphthyl)ethyl]imidazolium chloride.
• Solvent Use:In some contexts, it can be used as a specialized solvent. 

Important Safety and Handling Note:

Chloromethyl ethyl ether is a hazardous substance. It is considered harmful if inhaled, potentially causing respiratory irritation, dizziness, and central nervous system depression. It is also suspected of having carcinogenic or mutagenic properties. It should be stored in a cool, dry place, typically at 2-8°C.