Usage and Safety:
- Applications: Primarily used as an intermediate in solution-phase peptide synthesis and chemical biology. It has also been cited as a corrosion inhibitor.
- Hazard Identification: Classified as harmful if swallowed (H302) or inhaled (H332).
- Handling: Wear appropriate protective equipment (gloves, eyeshields, dust mask).
It is important to note that while this is a derivative of the nutrient amino acid, the chemical compound itself is intended for laboratory research and industrial use, not direct consumption.
L-Phenylalanine methyl ester hydrochloride (CAS 7524-50-7) is a white-to-off-white solid, also known as Methyl L-phenylalaninate hydrochloride, (S)-Phenylalanine methyl ester hydrochloride, and H-Phe-OMe·HCl. It is widely used in biochemical research, specifically for peptide synthesis, with the formula 𝐶10𝐻13𝑁𝑂2⋅𝐻𝐶𝑙.
Common Synonyms for CAS 7524-50-7:
- Methyl L-phenylalaninate hydrochloride
- (S)-Phenylalanine methyl ester hydrochloride
- H-Phe-OMe·HCl
- L-Phenylalanine, methyl ester, hydrochloride (1:1)
- (2S)-2-Amino-3-phenylpropionic acid methyl ester hydrochloride
- L-Phe-OMe·HCl
- Methyl (S)-phenylalaninate hydrochloride
- NSC 194642
Key Properties:
- Usage: Used in peptide synthesis, as a chiral building block, and in biochemical research.
L-Phenylalanine Methyl Ester Hydrochloride (CAS 7524-50-7) is a crucial chiral building block used primarily in peptide synthesis, pharmaceutical API development, and chemical research. As a C-protected amino acid, it enables selective, high-purity synthesis of active compounds. It is also used in biochemical studies, cosmetics, and as a flavor enhancer.
Key Uses and Applications
Peptide Synthesis: Functions as a key, C-protected building block for assembling complex peptides.
Pharmaceutical Intermediates: Utilized in the synthesis of APIs, particularly those targeting neurological disorders.
Chemical Research: Used in asymmetric synthesis and as a reagent for modifying functional groups.
Biochemical Studies: Employed in researching protein synthesis, metabolism, and amino acid behavior.
Cosmetics & Nutrition: Applied in cosmetic formulations for skin-soothing properties and occasionally in specialized animal feed additives.
Handling: Hygroscopic, requiring storage in a cool, well-ventilated area.
This compound ensures high optical integrity in manufacturing processes.
It is a derivative of L-Phenylalanine used as an intermediate in pharmaceutical and peptide synthesis. The CAS number is 7524-50-7, used for precise chemical identification. It is mainly used in drug development, peptide synthesis, and biochemical research. It is generally available in high purity, typically ≥98%, suitable for lab and industrial applications. It should be stored in a cool, dry place in tightly sealed containers away from moisture and light.
