L-Threonine Methyl Ester Hydrochloride CASNO:39994-75-7  

Properties

CAS Number: 39994-75-7

Molecular Weight: 169.61 g/mol

Appearance: White to pale yellow/yellowish powder or crystals

Melting Point: Approximately 64 °C (can vary depending on purity)

Solubility: Soluble in water, chloroform, dichloromethane, ethyl acetate, and DMSO

Stability: Moisture-sensitive and hygroscopic (should be stored under an inert atmosphere, typically in a freezer at -15°C to 0-8°C)

Synonyms

Methyl L-threoninate hydrochloride

L-Threonine, methyl ester, hydrochloride (1:1)

H-Thr-OMe·HCl

(2S,3R)-Methyl 2-amino-3-hydroxybutanoate hydrochloride

Methyl (2S,3R)-2-amino-3-hydroxybutanoate hydrochloride

L-Thr-OMe HCl

 

 

Uses and Applications

Pharmaceutical Development: Used in the synthesis of pharmaceuticals, particularly those targeting metabolic disorders, and studied for potential neuroprotective effects.
It is being investigated as a therapeutic agent for cancer, specifically for inhibiting tumor growth and inducing apoptosis.

Biotechnology & Peptide Synthesis: Functions as a protected amino acid building block (H-Thr-OMe·HCl) for constructing peptides and complex molecules.

Microbiology & Infection Research: Exhibits potent in vitro activity against Gram-negative bacteria, including Escherichia coli and Klebsiella pneumoniae, acting as a potential antimicrobial agent.

Biochemical Research: Used to study metabolic pathways and enzyme activity, serving as an agonist for the hyaluronic acid receptor.

Nutritional Supplements: Used in research regarding amino acid supplementation to enhance protein synthesis and muscle recovery.

Safety and Handling

Storage: Store in a dry, cool place (often required to be kept frozen/under inert gas) due to moisture sensitivity.

Hazards: May cause irritation to eyes, skin, and respiratory system. Generally classified under WGK 3 (hazardous to water). 

 

 

What is L-Threonine Methyl Ester Hydrochloride used for?

It is primarily used as an intermediate in peptide synthesis and pharmaceutical manufacturing.

What is the CAS number of this compound?

The CAS number is 39994-75-7.

Is this compound suitable for laboratory research?

Yes, it is commonly used in research labs for chemical and peptide synthesis.

How should L-Threonine Methyl Ester Hydrochloride be stored?

Store in a cool, dry place, tightly sealed, away from moisture and light.

What is the typical appearance of this compound?

It usually appears as a white to off-white crystalline powder.

FAQs

What is L-Threonine Methyl Ester Hydrochloride used for?

It is primarily used as an intermediate in peptide synthesis and pharmaceutical manufacturing.

What is the CAS number of this compound?

The CAS number is 39994-75-7.

Is this compound suitable for laboratory research?

Yes, it is commonly used in research labs for chemical and peptide synthesis.

How should L-Threonine Methyl Ester Hydrochloride be stored?

Store in a cool, dry place, tightly sealed, away from moisture and light.

What is the typical appearance of this compound?

It usually appears as a white to off-white crystalline powder.