2-Amino-5-Bromo-3-Nitro Pyridine (CAS 6945-68-2)

Physical Properties:

  • Appearance: Off-white to light yellow or tan powder/crystalline solid.
  • Molecular Formula: 𝐶5𝐻5𝐵𝑟𝑁2
  • .Molecular Weight: 173.01 g/mol.
  • Melting Point: 133-138 °C (literature).
  • Boiling Point: ~230.9 °C (predicted/approx.).
  • Solubility: Soluble in DMSO, methanol, chloroform, and Ethyl acetate; slightly soluble in water.
  • Physical State: Solid at room temperature (20°C).
  • Synonyms:
  • 5-Bromo-2-aminopyridine
  • 5-Bromo-2-pyridinamine
  • 5-Bromopyridin-2-ylamine
  • 5-Bromopyridin-2-amine
  • 2-Pyridinamine, 5-bromo-
  • Pyridine, 2-amino-5-bromo-

 

 

Uses:

  • Pharmaceuticals: A fundamental intermediate for synthesizing drugs, including potential anticancer, antibacterial, and antifungal agents.
  • Organic Synthesis: An important reagent for creating more complex molecules through various cross-coupling reactions (e.g., Suzuki, Heck).
  • Material Science: Used as a ligand in coordination chemistry to form metal complexes.
  • Research: Utilized in academic studies, such as investigating hydrogen-bonding patterns in co crystals and developing new polycyclic aromatic compounds.

 

 

Key Applications:

  • Pharmaceutical Intermediates: A crucial starting material for synthesizing new drug candidates, leveraging its reactive amino and bromo groups on the pyridine ring, note.
  • Agrochemicals: Used in developing pesticides and other crop protection agents.
  • Heterocyclic Synthesis: Essential for creating complex ring structures (azaarenes) in medicinal chemistry.
  • Biochemical Research: Employed in labeling techniques, such as labeling reducing-end oligosaccharides for study.
  • Material Science: Used in creating novel materials and as a catalyst ligand.

General Role:
It’s a halogenated pyridine derivative, acting as a valuable “building block” that chemists use to construct larger, more complex organic compounds for various industrial and research purposes.

FAQs

What is 2-Amino-5-Bromo-3-Nitropyridine (CAS 6945-68-2)?

2-Amino-5-Bromo-3-Nitropyridine is a substituted pyridine compound used as an important intermediate in pharmaceutical and fine chemical synthesis.

What are the applications of 2-Amino-5-Bromo-3-Nitropyridine?

It is widely used in the synthesis of pyridine-based APIs, pharmaceutical intermediates, agrochemical compounds, and medicinal chemistry research.

Is 2-Amino-5-Bromo-3-Nitropyridine used in pharmaceutical manufacturing?
Yes, it is commonly used in pharmaceutical and API research for developing active compounds and advanced intermediates.
Do you manufacture 2-Amino-5-Bromo-3-Nitropyridine in bulk quantities?
Yes, we manufacture and supply 2-Amino-5-Bromo-3-Nitropyridine (CAS 6945-68-2) in bulk and commercial quantities.
What purity grades are available for this product?

The product is available in high-purity grades suitable for pharmaceutical, laboratory, and specialty chemical applications.

FAQs

What is 2-Amino-5-Bromo-3-Nitropyridine (CAS 6945-68-2)?

2-Amino-5-Bromo-3-Nitropyridine is a substituted pyridine compound used as an important intermediate in pharmaceutical and fine chemical synthesis.

What are the applications of 2-Amino-5-Bromo-3-Nitropyridine?

It is widely used in the synthesis of pyridine-based APIs, pharmaceutical intermediates, agrochemical compounds, and medicinal chemistry research.

Is 2-Amino-5-Bromo-3-Nitropyridine used in pharmaceutical manufacturing?
Yes, it is commonly used in pharmaceutical and API research for developing active compounds and advanced intermediates.
Do you manufacture 2-Amino-5-Bromo-3-Nitropyridine in bulk quantities?
Yes, we manufacture and supply 2-Amino-5-Bromo-3-Nitropyridine (CAS 6945-68-2) in bulk and commercial quantities.
What purity grades are available for this product?

The product is available in high-purity grades suitable for pharmaceutical, laboratory, and specialty chemical applications.