Physical properties:

Appearance : White to light yellow crystalline solid or liquid

Melting Point: 29–33°C (84–91°F)

Boiling Point: 127–128°C at 15 mmHg; 183.7°C at 760 mmHg

Density: 1.498 g/

Flash Point: >110°C

Refractive Index: 1.5575

Molecular Weight: 215.04 g/mol

Solubility: Soluble in common organic solvents

Synonyms:

• 3-Bromobenzoic acid methyl ester
• Methyl m-bromobenzoate
• Benzoic acid, 3-bromo-, methyl ester
• Methyl-3-brombenzolcarboxylat

 Uses:

Pharmaceutical Intermediate: Used in the development of drugs, particularly in the synthesis of tetrahydrodibenzazocine derivatives.

Organic Synthesis Reagent: Acts as a building block for forming 1,1-diarylethane derivatives through cross-coupling with arylborates.

Chemical Synthesis: Used to prepare 3-tert-butylphosphanyl-benzoic acid methyl ester.

Research Chemical: Utilized for creating compounds that are chemically reactive to trifluoroacetic acid gas.

Key Applications:

Pharmaceutical Intermediate: Used in the synthesis of tetrahydrodibenzazocine, which acts as an inhibitor of 17

-hydroxysteroid dehydrogenase type 3.

Organic Synthesis & Reagent: Acts as a key intermediate for introducing the 3-bromobenzoate moiety into complex molecules.

Cross-Coupling Reactions: Employed in palladium-catalyzed reactions, including the Negishi coupling with diarylzinc reagents to create 1,1-diarylethane derivatives.

Agrochemical Production: Used as a precursor in the development and manufacturing of specialized agricultural chemicals.

Chemical Research: Used in research for developing new, functionalized aromatic compounds.