4-Chloroquinoline(CAS 611-35-8)

4-Chloro Quinoline (CAS 611-35-8)

Physical properties:

  • Appearance/Physical State: White to almost white powder to lump, which can also be a colorless liquid to solid (it has a low melting point close to room temperature).
  • Melting Point (mp): 28−31 ∘C.
  • Boiling Point (bp): 260−261 ∘C
  • Density: 25 g/mLat 20 ∘C.
  • Solubility: Partly soluble in water.
  • Synonyms:
  • Quinoline, 4-chloro-, 4-chloro-quinoline.
  • 4-Chloroquinoline.
  • 4-Chloroquinoline 97%,
  • 4-Chloroquinoline 99%.

 

Categories: ,

Uses:

  • Pharmaceuticals: A key intermediate for synthesizing drugs, especially antimalarial (e.g., chloroquine derivatives) and antibacterial agents, leveraging the biologically active quinoline ring structure.
  • Agrochemicals: Used in creating pesticides and other crop protection products.
  • Dyes & Pigments: An important raw material in the production of various dyes and coloring agents.
  • Material Science: Explored in developing advanced materials like durable polymers and protective coatings.
  • Organic Synthesis Research: A versatile building block for creating complex organic molecules for various research applications.
  • Analytical Chemistry: Employed as a reagent for detecting and quantifying other substances in laboratory settings.

The quinoline structure is a privileged scaffold in medicinal chemistry, and the chlorine atom at the 4-position provides a reactive site for further chemical modifications, making it ideal for creating diverse, biologically active compounds.

Key Applications:

  • Pharmaceuticals: A crucial precursor for synthesizing drugs, particularly antimalarial compounds, by modifying its structure to create active pharmaceutical ingredients (APIs).
  • Agrochemicals: Used in developing pesticides and herbicides to protect crops, offering effective pest control.
  • Dyes & Pigments: Serves as a raw material in the production of various dyestuffs, contributing to vibrant colors in textiles and other applications.
  • Organic Synthesis: Acts as a fundamental building block for creating complex organic structures, facilitating innovations in chemistry.
  • Material Science: Explored in creating new polymers and coatings with enhanced durability and resistance.
  • Analytical Chemistry: Employed as a reagent for detecting and quantifying other substances in laboratory settings for quality control.

Role in Research:

  • Biochemical Research: Used as a biochemical reagent for life science studies.
  • Chemical Building Block: Valued for its halogenated heterocyclic structure, making it useful in creating diverse chemical libraries for drug discovery and material innovation.

FAQs

What is 4-Chloroquinoline (CAS 611-35-8)?
4-Chloroquinoline is a halogenated quinoline compound used as an important intermediate in pharmaceutical and fine chemical synthesis.
What are the applications of 4-Chloroquinoline?
It is widely used in the synthesis of quinoline-based APIs, pharmaceutical intermediates, agrochemicals, and medicinal chemistry research.
Is 4-Chloroquinoline used in pharmaceutical manufacturing?
Yes, it is commonly used in pharmaceutical and API research for developing active compounds and advanced intermediates.
Do you manufacture 4-Chloroquinoline in bulk quantities?

Yes, we manufacture and supply 4-Chloroquinoline (CAS 611-35-8) in bulk and commercial quantities.

What purity grades are available for this product?
Yes, it is supplied for domestic and international markets with complete regulatory and export documentation

FAQs

What is 4-Chloroquinoline (CAS 611-35-8)?
4-Chloroquinoline is a halogenated quinoline compound used as an important intermediate in pharmaceutical and fine chemical synthesis.
What are the applications of 4-Chloroquinoline?
It is widely used in the synthesis of quinoline-based APIs, pharmaceutical intermediates, agrochemicals, and medicinal chemistry research.
Is 4-Chloroquinoline used in pharmaceutical manufacturing?
Yes, it is commonly used in pharmaceutical and API research for developing active compounds and advanced intermediates.
Do you manufacture 4-Chloroquinoline in bulk quantities?

Yes, we manufacture and supply 4-Chloroquinoline (CAS 611-35-8) in bulk and commercial quantities.

What purity grades are available for this product?
Yes, it is supplied for domestic and international markets with complete regulatory and export documentation

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